TETRAARSENIC TETRASULFIDE TRIGGERS ROS-INDUCED APOPTOSIS AND FERROPTOSIS IN B-CELL ACUTE LYMPHOBLASTIC LEUKAEMIA BY TARGETING HK2

Tetraarsenic tetrasulfide triggers ROS-induced apoptosis and ferroptosis in B-cell acute lymphoblastic leukaemia by targeting HK2

Purpose: Acute lymphoblastic leukemia (ALL) is the most common type of cancer diagnosed in children.Despite cure rates of higher than 85 %, refractory or relapsed ALL still exhibits a bleak prognosis indicative of the dearth of Dummies treatment modalities specific for relapsed or refractory ALL.Prior research has implicated metabolic alterations i

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Applying the Operational Design Domain Concept to Vehicles Equipped with Advanced Driver Assistance Systems for Enhanced Safety

Advanced driver assistance systems (ADASs) assist drivers by alerting them of the occurrence of events based on the sensing capabilities of the vehicle, reducing the effort required Terminal Release Set by drivers.Most vehicles that are recently launched vehicles have been endowed with ADAS, thereby significantly reducing traffic accidents.However,

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Is physician supervision of the capsaicin 8% patch administration procedure really necessary? An opinion from health care professionals

Kai-Uwe Kern,1 Janice England,2 Andrea Roth-Daniek,3 Till Wagner3 1Institute for Pain Medicine/Pain Practice, Wiesbaden, Germany; 2Pain Medicine and Anaesthesia, The Christie National Health Service Foundation Trust, Manchester, UK; 3Pain Therapy and Palliative Care Department, Medizinisches Zentrum Städteregion Aachen, Aachen, Germany Abstrac

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